Preformulation is a critical activity often overlooked in the development of new or existing medicines. At Azopharma, we specialize in the design and execution of pertinent preformulation activities required for successful pharmaceutical product development.

Service/Capabilities

Polymorph studies API salt selection Excipient-excipient compatibility API-excipient interaction studies pKa determination Hygroscopicity studies Phase-solubility determination Photostability of API Container-API interactions Extractables/Leachables

Solvate forms Solubility (water, solvents, log P) Zeta potential Particle size distribution - Malvern Pore size and surface area (nitrogen adsorption) Compaction properties (Hausner ratio, Carr's index) Compressibility Flowability (angle of repose) Intrinsic dissolution Wetability